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management rheumatology druginduced lupus causes comparison cop cryptogenic differential hemophagocytic hlh ild lymphohistiocytosis nephrology organizing pneumonia pulmonary rhabdomyolysis sle summary
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... constitutional symptoms • Treatment ... 40, F:M 9:1 • Clinical ... life-threatening • Treatment ... #rheumatology #diagnosis
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Differential Diagnosis ... - Seizures - Malignant ... - Neuroleptic malignant ... - Toxins - Drugs ... Dermatomyositis Clinical
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop ... of clinical and ... Assessment • Clinical ... immune deficiency, Drugs ... inhibitors under evaluation
Cryptogenic Organizing Pneumonia (COP) Cryptogenic Organizing Pneumonia Overview: • Idiopathic form of organizing pneumonia • formerly BOOP
pneumonia • formerly BOOP ... association with CTD, drugs ... , malignancy and ... Organizing Pneumonia - Clinical ... Organizing Pneumonia Treatment
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
to 1:1 F:M • Clinical ... Workup: - ANA ... • Evolution: ... #rheumatology #diagnosis ... #treatment #management
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