12 results
Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
Algorithm for the Evaluation ... Diagnosis #Management #Hematology ... #SickleCell #Complications ... Manifestations #Workup ... #Algorithm #Ddxof
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... function test, ANA ... - Bone marrow evaluation ... not required in all ... #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
lymphoproliferative disorders ... kinase (BTK) Complications ... leukemia • GI complications ... Leukemia #diagnosis #workup ... #oncology #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Consider sickle cell ... with or without platelet ... Consider RBC membrane disorder ... Diagnosis #Algorithm #workup ... #hematology #testing
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... Disorders • Nutritional ... Workup: • Complete ... Syndromes #diagnosis #hematology
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
, symptoms and complications ... generally requires all ... hemoproliferative disorder ... Thrombocythemia #ET #hematology ... diagnosis #management #hematology
Helpful Clinical Features in Evaluating Bleeding Disorders
Age of onset
 • Neonate - in 20% of haemophilias,
Clinical Features in Evaluating ... Bleeding Disorders ... relatives (if all ... characteristic of platelet ... pediatrics #diagnosis #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... • Autoimmune disorders ... Hodgkin Lymphoma Workup ... - Low Hb and platelets ... classification #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... first step in evaluation ... Connective tissue disorders ... gastric tumors • Hematology ... differential #diagnosis #hematology
Relapsing Polychondritis

What is it?
Recurrent inflammation of the cartilage in the body (Autoimmune disorder)

Who?
• Most frequently: 40
body (Autoimmune disorder ... Males • Affects all ... Large vessels (aorta ... Multiple myeloma Complications ... Nonspecific ↑ ESR, CRP, ANA