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diagnosis differential management rheumatology lupus anemia bleeding bruising comparison druginduced erythematosus hemolytic polychondritis relapsing summary systemic table testing thrombocytopenia
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
and Platelet Disorders ... Diagnosis and Workup ... (e.g., SLE), anti-phospholipid ... - Bone marrow evaluation ... #Workup #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Sequestration Disordered ... Platelet Function ... ASA) • Renal Disease ... #Causes #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... ): SS, SC, SE, Sβ ... with or without platelet ... Consider RBC membrane disorder ... #workup #hematology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
• Immunologic Workup ... : - ANA > ... Positive in 60-80% of cases ... • Evolution: ... Chronic disease
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... : - ANA > ... • Immunologic Workup ... Chronic disease ... comparison #table #rheumatology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
body (Autoimmune disorder ... Large vessels (aorta ... immunologically mediated diseases ... as: • SLE • RA ... Sarcoidosis • Behcet disease
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