8 results
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... during medical evaluation ... /µL Workup • Screen ... #Algorithm #Differential ... #diagnosis #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
lymphoproliferative disorder ... younger pts) Differential ... sensitize red blood cells ... chills, flank pain ... hemolytic #anemia #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential ... Diagnosis and Workup ... practices that could ... - Bone marrow evaluation ... #Workup #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Diagnosis Algorithm ... • Sickle cells ... Agglutination - Cold ... Consider RBC membrane disorder ... #workup #hematology
Aortic Dissection Pearls
Aortic dissection is caused by a tear in the tunica intima, the innermost layer
the wall of the aorta ... Evaluation: 1. ... Connective tissue disorder ... Pulse deficit/differential ... Aortic #Dissection #diagnosis
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... hemolytic anemia • Pain ... Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate ... classification #hematology
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
presents with pain ... Diagnosis? ... Biopsy: Solitary disorder ... Evaluation? ... #Workup #Hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... first step in evaluation ... Connective tissue disorders ... Gap #ProteinGap #differential ... #diagnosis #hematology