11 results
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... Disease (AOSD) ... salmon-colored maculopapular ... rash, arthritis ... : high fever, CRP
Maculopapular Rashes - THE ALGORITHMIC APPROACH 

The term maculopapule is a portmanteau, a combination
of macule and
appear toxic and febrile ... assessed for Lyme disease ... pathognomonic for SJS or EM ... require emergent evaluation ... #Rash #Algorithm
ID Approach to Fever and Rash - Diagnostic Algorithm
Central Maculopapular (most common):
Measles, Parvovirus 819 / EBV,
and Rash - Diagnostic ... Maculopapular ( ... Secondary syphilis, EM ... #Rash #Febrile ... #Diagnosis #Algorithm
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - ... Diagnostic Algorithm ... instability - New-onset ... fever with rash ... #Differential #Ddxof
Differential Diagnosis and Evaluation of Hyponatremia:
1) Identification of onset (acute vs. chronic)
2) Presence of symptoms (HA,
and Evaluation ... Identification of onset ... , liver, renal disease ... #EM #IM #Nephro ... #Ddxof
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... nonpruritic macular or maculopapular ... extremities during febrile ... anti-ILI #Adult #onset ... #AOSD #diagnosis
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH 

These rashes can be especially challenging and are
associated with devastating differential
in vasculitic diseases ... petechiae/purpura with fever ... require emergent evaluation ... the patient is afebrile ... Purpural #Purpuric #Rash
Algorithm for the Evaluation of Kawasaki and Incomplete Kawasaki Disease:
Diagnosis
* Fever >5d
* Criteria (4/5)
  -
Algorithm for the ... Evaluation of Kawasaki ... Fever >5d * Criteria ... , >1.5cm) - Rash ... #Ddxof
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
< 30 years • Aorta ... Arteritis): • Aorta ... , mucositis • Rash ... Nervous System: • Onset ... vesicles, pustules, maculopapular
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Mediated: • Febrile ... /sx urticaria, maculopapular ... rash, pruritis, ... resembles ARDS, onset ... #Transfusion #diagnosis