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anemia hematology algorithm differential macrocytic management aafp aplastic causes cobalamin elevatedmcv folate folicacid homocysteine mma neutrophil nutrition oncology pathophysiology vitamin
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
- Differential Diagnosis ... Neutrophils - Low RBC ... • Dietary Deficiency ... and Folate Deficiency ... #Macrocytosis #
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
Algorithm for the evaluation ... (RBC = red blood ... deficiency is present ... deficiency. ... #Diagnosis #Macrocytosis
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... related to IBD, celiac ... total body stores Evaluation ... • Labs: - CBC ... hypersegmented neutrophils, macrocytosis
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Differential Diagnosis ... article/S0002-9343(12 ... tachycardia or fever ... count on initial evaluation ... #CBC #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Presentation: • Fever ... recurrent infections/fevers ... , GATA2 deficiency ... , CTLA4 deficiency ... #diagnosis #management
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