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rheumatology differential management approach comparison lupus msk pain sle antimda5 antimda5dm cppd dermatology dermatomyositis druginduced erythematosus gap globulin gout laboratory
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Pain - Diagnostic ... ), RA, crystal disease ... #rheumatology # ... approach #workup ... #differential #diagnosis
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Disease: • Pain ... disease must be ... #Pain #MSK #rheumatology ... #approach #workup ... #differential #diagnosis
Septic Arthritis - Diagnosis and Management Summary Clinical Exam: hot, swollen, pain with passive AND active ROM
necrosis, Lyme disease ... Workup: arthrocentesis ... count, and crystal evaluation ... until proven otherwise ... MH/CCF/CWRU EM
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... of the affected joint ... (to support a diagnosis ... #laboratory #workup ... #diagnosis #testing
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
• Underlying disease ... culture used to diagnose ... • ↑ C-reactive protein ... Gout #Comparison #rheumatology ... #Diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Malignancy (e.g. hematologic ... : • Joint pain ... arthropathy • 90% joints ... pancreatitis, protein-losing
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... vesicular eruption • Joints ... with elevated protein ... Palpable purpura, joint ... #Rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... • Immunologic Workup ... • Immunologic Workup ... : Chronic disease ... #diagnosis #management
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
interphalangeal joints ... of C-reactive protein ... severity of the disease ... • Arthralgia/arthritis ... #dermatology #diagnosis
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary WHAT? • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
• An evaluation ... for giant cell arteritis ... Also consider an evaluation ... and C-reactive protein ... #Management #Rheumatology
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