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diagnosis algorithm management aafp cobalamin folate folicacid hematology homocysteine ibd macrocytic macrocytosis mds myelodysplasia myelodysplastic nutrition oncology syndromes vitamin vitaminb12
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
Algorithm for the evaluation ... red blood cell; MMA ... the most likely cause ... recovery also causes ... deficiency.
Fatigue and IBD Algorithm • 40-50% patients have fatigue despite clinical remission • Risk factors: BMI,
Crohn's > UC Anemia ... (B12, MMA) for ... restricted diet/deficiency ... despite disease ... /other causes •
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
• Common Causes ... slowing, neuropathy, fatigue ... related to IBD, celiac ... disease, other ... - Elevated MMA
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Symptoms: • Fatigue ... Myeloproliferative Disease ... Nutritional: vitamin B12 ... Workup: • Complete
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