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diagnosis differential b12 cell cobalamin deficiency gap globulin management nutrition oncology plasmacytoma platelet protein proteingap solitary thrombocytopenia vitamin
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... . pylori test (GI ... changes), high MCV anemia ... - Bone marrow evaluation ... #Workup #hematology
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
• Common Causes ... dysfunction, and/or disorders ... skin pallor • GI ... related to IBD, celiac ... total body stores Evaluation
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... first step in evaluation ... Connective tissue disorders ... gastric tumors • Hematology ... Thalassemia, Sickle cell anemia
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Less common - GI ... Biopsy: Solitary disorder ... • No CRAB - no anemia ... Diagnostic Evaluation ... #Hematology
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