24 results
Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
Algorithm for the Evaluation ... of Sickle Cell Crises ... Clinical Manifestations ... Workup #Algorithm #Ddxof
Invasive Aspergillus (IA) - Diagnosis and Management
Aspergillus is ubiquitous in nature. Most invasive infections are caused
are caused by members ... HIV/AIDS, CGD) Clinical ... , Disseminated infection ... considered in certain cases ... treatment #fungal #infectiousdiseases
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Triggering factor (infection ... accumulation of clinical ... Assessment • Clinical ... Drugs, Unknown cause ... inhibitors under evaluation
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
Infection with ... BCNIE relies on evaluation ... antimicrobials, clinical ... but important causes ... differential #workup #infectiousdiseases
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Can present in middle ... to 8 years Clinical ... history of recurrent infections ... disease • Infectious ... DDX - Other causes
Tuberculosis Testing

LATENT TB
• LTBI is diagnosed when an asymptomatic patient has a positive TST or IGRA
result with no clinical ... developing active infection ... • Tuberculosis infection ... smear-positive sputum sample ... LatentTB #ActiveTB #InfectiousDiseases
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
should be based on clinical ... presentation, temporal evolution ... present in 15% of cases ... Demyelinating disease caused ... opportunistic #InfectiousDiseases
Waterborne Infections - Differential Diagnosis Framework

Infections that can be acquired from fresh water, brackish water, sea
Waterborne Infections ... Diagnosis Framework Infections ... is biphasic • Clinical ... - And, in rare cases ... Differential #Diagnosis #InfectiousDiseases
Hearing Loss - Differential Diagnosis Framework

Hearing Loss Types:
• Conductive
• Sensorineural
• Mixed
Presbycusis is the most common type
The evaluation should ... Infection or cancer ... Otitis externa • Middle ... cause unknown) ... ○ MS, CVA • Infectious
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
Causes of spinal ... • Extrinsic Causes ... Infarction - Infection ... Impotence - Saddle ... Sensory loss - Saddle