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classification differential hemophagocytic hlh lymphohistiocytosis management peds sbi seriousbacterialillness summary treatment vasculitis
Serious Bacterial Illness (SBI): 1) UTI and pyelonephritis Most common cause of SBI Accounts for 3-8% of uncharacterized fevers Female
pyelonephritis Most common cause ... uncharacterized fevers ... Consider BCx, CSF evaluation ... #Peds #EM #Classification ... #Ddxof
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... • Clinical: fever ... Drugs, Unknown cause ... inhibitors under evaluation ... treatment #summary #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... mononeuritis multiplex • GI ... rhinitis/sinusitis, saddle ... tract, and often causes ... #Rheumatology
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