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diagnosis differential hematology algorithm hypertension adrenal common cvid early endocrinology eosinophil eosinophilia gap globulin hearing hypogammaglobulinemia immunodeficiency immunology indications insufficiency
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... PT, aPTT(liver disease ... bypass), LFT (liver disease ... - Bone marrow evaluation ... #Workup #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... during medical evaluation ... or workup for specific ... • Screen for secondary ... (common causes
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
Causes of Secondary ... Hypertension - Workup ... Approach (when evaluation ... Renal parenchymal disease ... Neurologic disorders
Approach to a young patient with hypertension General Evaluation - History and Examination, Basic chemistries (K, eGFR),
hypertension General Evaluation ... ↑AIdo/↑PRA: Secondary ... Cushing, CAH, AMES, Liddle ... apnea, thyroid disease ... #workup #algorithm
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... infection risk secondary ... Can present in middle ... • Chronic lung disease ... DDX - Other causes
Primary Adrenal Insufficiency: • ACTH stimulation test - Synthetic ACTH does not stimulate cortisol secretion because
aldosterone - Low in cases ... origin of the disorder ... a hypothalamic disorder ... Insufficiency #Evaluation ... endocrinology #workup
Hearing Loss - Differential Diagnosis Framework Hearing Loss Types: • Conductive • Sensorineural • Mixed Presbycusis is the most common type
The evaluation should ... Onset ○ Meniere disease ... cause unknown) ... Mitochondrial disorders ... ○ HIV ○ Lyme disease
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... DDX: Rule Out Secondary ... Myeloproliferative Disease ... Workup: • Complete
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... first step in evaluation ... • Heavy chain disease ... Connective tissue disorders ... Sarcoidosis) • Liver disease
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