8 results
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... during medical evaluation ... or workup for specific ... • Screen for secondary ... eosinophilia (common
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Common Variable ... Immunodeficiency disorder ... infection risk secondary ... Can present in middle ... cancers: Most common
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Causes of Secondary ... Hypertension - Workup ... Approach (when evaluation ... Renal parenchymal disease ... Neurologic disorders
Approach to a young patient with hypertension
General Evaluation - History and Examination, Basic chemistries (K, eGFR),
hypertension General Evaluation ... ↑AIdo/↑PRA: Secondary ... Cushing, CAH, AMES, Liddle ... apnea, thyroid disease ... #workup #algorithm
Primary Adrenal Insufficiency:
 • ACTH stimulation test - Synthetic ACTH does not stimulate cortisol secretion because
The most commonly ... origin of the disorder ... a hypothalamic disorder ... Insufficiency #Evaluation ... endocrinology #workup
Hearing Loss - Differential Diagnosis Framework

Hearing Loss Types:
• Conductive
• Sensorineural
• Mixed
Presbycusis is the most common type
Presbycusis is the most common ... The evaluation should ... - is the most common ... Mitochondrial disorders ... ○ HIV ○ Lyme disease
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... Most common cytopenia ... DDX: Rule Out Secondary ... Myeloproliferative Disease
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... first step in evaluation ... • Heavy chain disease ... Connective tissue disorders ... Comment on type