35 results
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
of Old and New Potassium-Binding ... edgarvlermamd #Potassium ... KBinders #Kayexelate #Comparison ... #Table #Pharmacology ... #Patiromer #HyperKalemia
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Agents to Treat Hyperkalemia ... to moderate); hypokalemia ... #Binding #Hyperkalemia ... #medications #pharmacology ... #table #comparison
Diuretics sites of action on the nephron
1) Acetazolamide (carbonic anhydrase inhibitor)
2) Osmotic diuretics (e.g. mannitol)
3) Loop
(e.g. ... Metolazone) 5) Potassium-sparing ... diuretics (e.g. ... #pharmacology # ... nephrology #medications
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Hypokalemia - Differential ... Thyrotoxicosis Medications ... • Discontinued diuretic ... MatthewHoMD #Hypokalemia ... nephrology #low #potassium
Compelling and Possible Contraindications to Antihypertensive Drugs
Diuretics (thiazides)
 - Gout
 - Metabolic syndrome, Glucose intolerance, Pregnancy,
, Hypokalemia, Erectile ... antagonists (MRA) - Hyperkalemia ... higher risk of hyperkalemia ... Angioneurotic edema, Hyperkalemia ... - Pregnancy, Hyperkalemia
Medications for the Treatment of Hyperkalemia
The goals of acute treatment are to prevent potentially life-threatening cardiac
the Treatment of Hyperkalemia ... , changes on ECG ... , severe hyperkalemia ... , and Table 3 summarizes ... #Hyperkalemia #
Hypokalemia - Differential Diagnosis
Poor Intake 
 - Starvation
 - Anorexia
GI Losses 
 - Vomiting / NG
Hypokalemia - Differential ... Urinary Losses - Diuretics ... DrEricStrong #Hypokalemia ... Diagnosis #Low #Potassium ... #Table #Classification
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Summary of Diuretic ... Chlorthalidone POTASSIUM-SPARING ... Tolvaptan #Diuretics ... #Medications #Pharmacology ... #summary #table
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... Management of Hyperkalemia ... Binders #Management #Hyperkalemia ... #treatment #pharmacology ... #table #comparison
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Increased EC ... MunerMohamed1 #hyperkalemia ... pathophysiology #pharmacology ... #potassium #medications