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diagnosis diabetes differential disorders ketoacidosis ketosis algorithm comparison crisis diabetic diabeticketoacidosis dm2 eudka hhs hyperglycemic inhibitors nephrology sglt2i table
Ketosis Disorders - Comparison Table • Starvation Ketosis • Alcoholic Ketoacidosis (AKA) • Diabetic Ketoacidosis (DKA)
) • Euglycemic ... DKA • Hyperglycemic ... State (HHS) • DKA ... differential #diagnosis #management ... #endocrinology
Ketosis Disorders Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
• Euglycemic ... • DKA/HHS Overlap ... features of both DKA ... differential #diagnosis #management ... #endocrinology
Pathophysiology of Euglycemic DKA in SGLT2 Inhibitors • Kidney: Glycosuria, Natriuresis, ↑ Ketone bodies reabsorption •
Pathophysiology ... of Euglycemic DKA ... Natriuresis, ↑ Ketone ... DKA Dr priti ... #pathophysiology
Hyperglycemic Crisis - Algorithm for DKA/HHS Diagnostic criteria for DKA: • pH < 7.3 • Anion gap
Algorithm for DKA ... • Urine/serum ketones ... • Urine/serum ketones ... Crisis #Algorithm #management ... #endocrinology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
neuronal metabolism, ketone ... to a day after ketosis ... breathing) • Ketone ... #pathophysiology ... #endocrinology
Euglycemic Diabetic Ketoacidosis (EuDKA) SGLT2 Inhibitors Increasing Indications Significant Adverse Drug Effects Definition of EuDKA • Metabolic acidosis with pH
Euglycemic Diabetic ... level < 200 mg/dL Pathophysiology ... @accpcardprn #Euglycemic ... EuDKA #diagnosis #management ... #endocrinology
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