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rheumatology autoantibodies differential lupus table associations disease diseases erythematosus symptoms syndrome ana antibody antineutrophil antinuclear arthritis behcet classification comparison druginduced
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
• Lupus (SLE): ... antibodies) • ... Anti-cardiolipin (aCl ... • Scleroderma (Systemic ... Vasculitis: P-ANCA
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
) • Systemic lupus ... in drug-induced SLE ... ) • Systemic sclerosis ... Vasculitis: • ... #diagnosis #rheumatology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
syndrome Anti-Scl ... - Vasculitis, e.g ... Associations #diseases #diagnosis ... #table #rheumatology ... #antibodies
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... purpura: strong sign ... ) pattern: antibodies ... , and SLE) • Urinalysis ... #rheumatology #
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Auto-Antibodies ... : - ANA 95-100% ... #Systemic #Lupus ... autoantibodies #signs
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... erythematosus (ACLE ... Differential Diagnosis ... -70, RNP antibodies ... Erythematosus #Diagnosis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... Differential Diagnosis ... diseases, such as SLE ... purpura: Strong sign ... #Rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
thiazidic, PPI, ACE ... months to years) Systemic ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... affected joint • Systemic ... double-stranded DNA antibodies ... (to support a diagnosis ... laboratory #workup #diagnosis
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome Systemic ... Oral aphthae : SLE ... • Arthritis: SLE ... #management #signs ... #symptoms #rheumatology
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