18 results
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Hemophagocytic Lymphohistiocytosis ... : HLH signs and ... Ferritin >500 ng/mL ... #diagnosis #management ... #treatment #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Hemophagocytic Lymphohistiocytosis ... Drugs, Unknown cause ... Hemophagocytic #Lymphohistiocytosis ... #diagnosis #management ... treatment #summary #rheumatology
Hypertension in Anesthesiology - Differential Diagnosis and Management 

Initial checklist: 
 - Verify BP (e.g. surgeon
- Differential Diagnosis ... and Management ... Initial checklist ... Check other vital signs ... #Management #Checklist
Cardiac Tamponade - Guidelines for Crises in Anaesthesia
Caused by an accumulation of blood, pus, effusion fluid
examination and vital signs ... Plan definitive management ... Anesthesiology #Anesthesia ... Intraoperative #Checklist ... #Diagnosis #Management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
haemophagocytic lymphohistiocytosis ... (HLH) that develops ... 5000 to 10,000 ng/mL ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
maintained fever CAUSES ... hyperthermia crisis (late sign ... #Differential #Causes ... #Checklist #Diagnosis ... #Management #Workup
Hypotension - Guidelines for Crises in Anaesthesia

Hypotension is commonly due to unnecessarily deep anaesthesia, the autonomic
pressure as a cause ... fluid boluses (250 ml ... Anesthesiology #Anesthesia ... Intraoperative #Checklist ... #Diagnosis #Management
Intraoperative Circulatory Embolus - Guidelines for Crises in Anaesthesia
Causes: thrombus, fat, amniotic fluid, air/gas.
Signs: hypotension, tachycardia,
Causes: thrombus ... Signs: hypotension ... Anesthesiology #Anesthesia ... Intraoperative #Checklist ... #Diagnosis #Management
Intraoperative Anaphylaxis - Guidelines for Crises in Anaesthesia
• Unexplained hypotension
• Unexplained bronchospasm (wheeze may be absent
of more of the signs ... 4 ⓫ Take 5-10 ml ... Anesthesiology #Anesthesia ... Intraoperative #Checklist ... #Diagnosis #Management
Intraoperative Cardiac Ischaemia - Guidelines for Crises in Anaesthesia

If the patient is unconscious, signs of cardiac
Guidelines for Crises ... is unconscious, signs ... Anesthesiology #Anesthesia ... Intraoperative #Checklist ... #Diagnosis #Management