14 results
rheumatology hemophagocytic hlh lymphohistiocytosis disease oncology symptoms activation anemia anticoagulation antinxp2 antinxp2dm antiphospholipid aplastic aps behcet calcium cppd deposition dermatology
Antiphospholipid Syndrome (APS) APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid Syndrome ... Anticardiolipin antibodies (aCL ... to be present Treatment ... target to 3-4 • DOACs ... #management #anticoagulation
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... : HLH signs and ... Ferritin >500 ng/mL ... #management #treatment ... #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
WBC >100k, + lab signs ... organ damage • Treatment ... Low calcium • Treatment ... #TLS #diagnosis ... #management #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
) Differential Diagnosis ... Arthritis, AS Treatment ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
anemia, GATA2 deficiency ... , CTLA4 deficiency ... aplastic anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
sIL-2R >2400 Ul/ml ... Cellular immune deficiency ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... 5000 to 10,000 ng/mL ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelogenous Leukemia (CML ... or folic acid deficiency ... factor (GCSF) treatments ... • Copper deficiency ... #diagnosis #hematology
Clinical Feature of Hypomagnesemia and Magnesium Deficiency • Electrolyte Disturbance: Hypokalemia, Hypocalcemia • Neuromuscular and central
and Magnesium Deficiency ... Chronic fatigue syndrome ... Hypomagnesemia #diagnosis ... #signs #symptoms ... #Treatment #management
Gout - Diagnosis and Management Summary 3 Conditions for Gout to Manifest: 1. Hyperuricemia 2. Monosodium urate deposition in
and Management ... sex • Metabolic syndrome ... double contour sign ... #management #treatment ... #rheumatology
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