6 results
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
chest (in a V-sign ... dorsal part of the MCP ... Inverse Gottron’s sign ... #rheumatology # ... dermatology #diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... (CVID, WAS), (neurologic ... changes), high MCV ... #Differential #Diagnosis ... Causes #Workup #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Presentation / Diagnosis ... : HLH signs and ... Diagnosis via genetic ... Ferritin >500 ng/mL ... management #treatment #hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... artery aneurysms Diagnosis ... ) Differential Diagnosis ... #management #signs ... #symptoms #rheumatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
(HCV) • CLL & MBL ... et diutinum Neurologic ... Evans • ITP • Cl-NH ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
chest (in a V-sign ... dorsal part of the MCP ... : • ILD was diagnosed ... #rheumatology # ... dermatology