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hematology management oncology behcet causes chronic cll differential disease hemophagocytic hlh leukemia leukostasis lymphocytic lymphohistiocytosis lysis mds myelodysplasia myelodysplastic nephrology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... fever - ACS, AKI ... WBC >100k, + lab signs ... #TLS #diagnosis ... #management #hematology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Differential Diagnosis ... : • Triad of symptoms ... declines > ALT) • AKI ... + myoglobin AKI ... #nephrology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... CNS symptoms (headache ... Arthritis, AS Treatment ... #signs #symptoms ... #rheumatology #
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... : HLH signs and ... symptoms can mimic ... Ferritin >500 ng/mL ... #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... microglobulin Treatment ... #workup #oncology ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... age 70 years Symptoms ... Myelogenous Leukemia (CML ... Workup: • Complete ... #diagnosis #hematology
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