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rheumatology dermatomyositis hematology activation anticoagulation antimda5 antimda5dm antinxp2 antinxp2dm antiphospholipid guidelines hemophagocytic hlh lymphohistiocytosis macrophage mas treatment
Antiphospholipid Syndrome (APS) APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid Syndrome ... of 1 clinical event ... target to 3-4 • DOACs ... #APS #diagnosis ... #management #anticoagulation
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
dorsal part of the MCP ... auricular papules Clinical ... Lung Manifestations ... #rheumatology #dermatology ... #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... : HLH signs and ... #management #treatment ... #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
cytokines, such as ... Clinical Presentation ... rash) • Heart, lung ... 5000 to 10,000 ng/mL ... #Diagnosis #Management
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
chest (in a V-sign ... auricular papules Clinical ... Non-small-cell lung ... #management #rheumatology ... #dermatology
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