8 results
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Hemophagocytic Lymphohistiocytosis ... : HLH signs and ... Ferritin >500 ng/mL ... #management #treatment ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Hemophagocytic Lymphohistiocytosis ... sIL-2R >2400 Ul/ml ... Taar #HLH #Hemophagocytic ... #management #treatment ... #summary #rheumatology
Metatarsal Gout on POCUS

Painful and swollen 1st metatarsal. Double contour sign. Diagnosis? Gout. 

Global Ultrasound Institute
Double contour sign ... Diagnosis? ... Global Ultrasound ... #clinical #rheumatology ... #ultrasound
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
A subset of hemophagocytic ... 5000 to 10,000 ng/mL ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
knees, shoulders Signs ... narrowing) • Ultrasound ... Diagnosis: CLINICAL ... DIAGNOSIS based ... #management #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
artery aneurysms Diagnosis ... ) Differential Diagnosis ... Behcet #Syndrome #diagnosis ... #management #signs ... #symptoms #rheumatology
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
and Management ... not possible • Ultrasound ... double contour sign ... +Radiographic signs ... #rheumatology
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
chest (in a V-sign ... shoulders (in a shawl sign ... dorsal part of the MCP ... Dermatomyositis #diagnosis ... #management #rheumatology