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dermatology dermatomyositis hematology lupus sle syndrome treatment antimda5 antimda5dm antinxp2 antinxp2dm behcet comparison disease druginduced gout hemophagocytic hlh lymphohistiocytosis macrophage
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... 5000 to 10,000 ng/mL ... #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Non-autoimmune rheumatologic ... La, anti-Jo-1, SCL ... Chronic B-cell activation ... #Diagnosis #Rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
artery aneurysms Diagnosis ... ) Differential Diagnosis ... Behcet #Syndrome #diagnosis ... #management #signs ... #symptoms #rheumatology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
with edema • Erythematous ... dorsal part of the MCP ... • Arthralgia/arthritis ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... • Immunologic Workup ... Systemic Lupus Erythematosus ... comparison #table #rheumatology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
excessive macrophage activation ... : HLH signs and ... Ferritin >500 ng/mL ... #management #treatment ... #hematology
Gout - Diagnosis and Management Summary 3 Conditions for Gout to Manifest: 1. Hyperuricemia 2. Monosodium urate deposition in
and Management ... frequent attacks • Arthritis ... double contour sign ... +Radiographic signs ... #rheumatology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
with edema • Erythematous ... chest (in a V-sign ... shoulders (in a shawl sign ... dorsal part of the MCP ... #management #rheumatology
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