15 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... for workup, including ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... #Algorithm #hematology
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis)
Major criteria 
 1. Abrupt onset of tender
Diagnostic Criteria ... for Sweet Syndrome ... (Acute Febrile ... Excellent response to treatment ... #Acute #Febrile
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... febrile neutrophilic ... fluid overload, PCC ... #management #hematology
Algorithm for Management of Acute Exacerbation of COPD (AECOPD)

Obtain workup for alternate diagnoses and relevant comorbidities:
Algorithm for Management ... of Acute Exacerbation ... AECOPD) Obtain workup ... COPD Assess ... #Exacerbation #treatment
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- ACS, AKI, acute ... organ damage • Treatment ... : - If febrile ... #TLS #diagnosis ... #management #hematology
Fever Patterns - Differential Diagnosis Framework

Continuous Fever:
Temp > 38°C with only 1 degree fluctuation in 24
- Differential Diagnosis ... pneumonia • Acute ... infections • Acute ... Leptospirosis Pel-Ebstein ... #Differential #Diagnosis
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... presents as an acute ... or subacute febrile ... • Bicytopenia Treatment ... #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
microglobulin Treatment ... • Richter’s Syndrome ... ’s lymphoma or acute ... #workup #oncology ... #hematology
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
spine • MCC- acute ... Differential Diagnosis ... Spinal infection/abscess ... axial T1 and T2 Treatment ... #differential #diagnosis
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Acute febrile ... , breast CA - Hematologic ... Leukemia cutis Diagnosis ... Treatment: - Systemic ... #diagnosis #dermatology