12 results
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
alkalosis • Normal/low ... Bartter syndrome, Gitelman ... Urine chloride is ... #nephrology #differential ... #diagnosis
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Primary Metabolic ... - Differential Diagnosis ... Urine Cl-: Vomiting ... Bartter Syndrome, Gitelman ... #Algorithm #nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
thiazide-sensitive sodium-chloride ... nephron → - ↑ K+ ... → Hypokalemia Metabolic ... Pathophysiology #nephrology ... #diagnosis
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic ... - Differential Diagnosis ... Urine Cl-: Vomiting ... Bartter Syndrome, Gitelman ... #Algorithm #Nephrology
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
Urine K+ <13 mEq ... Urine Cl - Non-reabsorbable ... Bartter syndrome, Gitelman ... differential #algorithm #diagnosis ... #nephrology
Normal Anion-Gap Acidosis (NAGMA) - Differential Diagnosis Framework and Workup

NAGMA
- Chem, ABG or VBG
- Calculate Anion
- Differential Diagnosis ... Chloride Intoxication ... NonAnionGap #Acidosis #Metabolic ... #Differential #Diagnosis ... #Workup #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
thiazide-sensitive sodium ... alkalosis • Normal or low ... Hypocalciuria (spot urine ... #Syndrome #diagnosis ... #nephrology #management
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
A urine K/Cr ratio ... Bartter syndrome, Gitelman ... #Hypokalemia #diagnosis ... differential #potassium #nephrology ... #low
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison

Composition of LR:
 • Sodium 130 mEq/L
 •
trial • Minimal K ... same line - Citrate ... development of metabolic ... decreased renal blood flow ... Decreased GFR, urine
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic ... - Differential Diagnosis ... Urine Cl-: Vomiting ... Bartter Syndrome, Gitelman ... #Algorithm #Nephrology