9 results
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Inherited Defects ... of epithelial sodium ... Defects #Kidney #Nephrology ... #Diagnosis #Differential ... #Table
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
, Gitelman syndrome ... sodium is typically ... the excretion of sodium ... #Algorithm #nephrology ... #differential #diagnosis
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
volume-based algorithm Urine ... Cirrhosis, Nephrotic syndrome ... #differential #diagnosis ... #table #sodium ... #nephrology
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
Hyponatremia - Diagnosis ... Measure urine osmolality ... demyelination syndrome ... #Differential #Diagnosis ... #nephrology #sodium
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Differential Diagnosis ... Weakness - Dark urine ... hour with goal urine ... per day until stable ... #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Inherited (AR) ... thiazide-sensitive sodium ... Hypocalciuria (spot urine ... Rhabdomyolysis Treatment ... #diagnosis #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Antibiotics (Bactrim, PCN ... tourniquet / IVF line draw ... lysis) ± Urine ... Elimination (see Table ... #potassium #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Diagnosis of ... Inhibitors of Na+K+2Cl ... Tolvaptan) • Treatment ... Excretion #Diuresis #Nephrology ... #Medications #Table
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Hepatorenal Syndrome ... • Urine sodium ... Treatment Overview ... #Hepatorenal #Syndrome ... #Hepatology #Nephrology