1433 results
Metformin 
Current Renal Dose Adjustments due to Risk of Lactic Acidosis 
> 60 No adjustment 
45-60
45-60 Monitor eGFR ... #Dosing #Dose #Pharmacology ... #Diabetes
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... not initiate if eGFR ... not continue if eGFR ... #Metformin #Pharmacology ... #Summary #DM2 #diabetes
Metformin in Diabetic Kidney Disease
Immediate release:
 • Initial 500 mg or 850 mg once daily
 •
Metformin in Diabetic ... maximum dose eGFR ... recommended dose eGFR ... Metformin #CKD #pharmacology
Management of Diabetes Mellitus in Patients With CKD

1. Monitor for changes in BP, serum creatinine, &
Management of Diabetes ... T2D, CKD, & an eGFR ... evidence-based pharmacologic ... #Diabetes #CKD # ... ADA #KDIGO #eGFR
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
SGLT2 Inhibitors - Pharmacology ... Contraindications: eGFR ... • Euglycemic diabetic ... SGLT2 #Inhibitors #Pharmacology ... #Summary #DM2 #diabetes
Summary of dosing recommendations in renal impairment of commonly used hypoglycaemic agents

#Diabetes #Diabetic #Medications #Pharmacology #Dosing
hypoglycaemic agents #Diabetes ... #Diabetic #Medications ... #Pharmacology # ... Impairment #CKD #Table #GFR
The GFR Clock for Staging CKD

Staging CKD is most frequently done by calculating the estimated glomerular
The GFR Clock for ... function rate (eGFR ... calculating the eGFR ... to remember the eGFR ... #Nephro #CKD #EGFR
Summary table of mechanism of action, side effect and contraindications of commonly used diabetic drugs. 

#pharmacology
commonly used diabetic ... #pharmacology #dm2 ... #diabetes #medications
Diabetic Peripheral Neuropathy - Pharmacotherapy

Peripheral neuropathy is a common microvascular complication of diabetes. In clinic patients
Diabetic Peripheral ... complication of diabetes ... Peripheral #Neuropathy #Diabetes ... #Pharmacology #
Diabetic Nephropathy: Pathogenesis
 - Metabolic Pathway
 - Hemodynamic Pathway

#Diabetic #Nephropathy #Diabetes #pathophysiology
Diabetic Nephropathy ... Hemodynamic Pathway #Diabetic ... #Nephropathy #Diabetes