102 results
The GFR Clock for Staging CKD

Staging CKD is most frequently done by calculating the estimated glomerular
The GFR Clock for ... function rate (eGFR ... calculating the eGFR ... Using the GFR clock ... #Nephro #CKD #EGFR
Summary of dosing recommendations in renal impairment of commonly used hypoglycaemic agents

#Diabetes #Diabetic #Medications #Pharmacology #Dosing
hypoglycaemic agents #Diabetes ... #Diabetic #Medications ... Impairment #CKD #Table #GFR
Interpreting Kidney Biomarkers

↑ Creatinine: 
 • AKI, CKD
 • Medications that lead to nephroprotective ↓ in
nephroprotective ↓ in GFR ... hyperthyroidism ↓ eGFR
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
not initiate if eGFR ... not continue if eGFR ... mL/minute/1.73 m2 ... Pharmacology #Summary #DM2 ... #diabetes #endocrinology
Definitions of AKI, CKD, AKD
Acute Kidney Injury (AKI):
 • Increase in SCr by 2 50% within
Disease (CKD): • GFR ... ml/min per 1.73 m2 ... • AKI, OR • GFR ... • Decrease in GFR ... Disease (NKD): • GFR
To improve the usefulness of the serum creatinine concentration as a marker of kidney function, prediction
accurately predict GFR ... overestimation of GFR ... used to estimate GFR ... CockcroftGault #EGFR
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
Contraindications: eGFR ... mL/minute/1.73 m2 ... • Euglycemic diabetic ... Pharmacology #Summary #DM2 ... #diabetes #endocrinology
Renal Failure Prognosis - The eGFR and proteinuria offers a general prognosis as demonstrated in the
Prognosis - The eGFR ... #CKD #EGFR #Proteinuria
Regulation of GFR
Physiologically, GFR is auto-regulated very precisely with changes in the mean arterial pressure (MAP)
Regulation of GFR ... Physiologically, GFR ... Pathophysiology #Nephrology #GFR
Summary table of mechanism of action, side effect and contraindications of commonly used diabetic drugs. 

#pharmacology
commonly used diabetic ... #pharmacology #dm2 ... #diabetes #medications