1318 results
Management of Diabetes Mellitus in Patients With CKD

1. Monitor for changes in BP, serum creatinine, &
initiation of treatment ... FDA recommends, metformin ... T2D, CKD, & an eGFR ... CKD #ADA #KDIGO #eGFR ... #Insulin #metformin
Patient factors influencing the selection Of glucose-lowering drugs Other than SGLT2i and metformin in T2D and
than SGLT2i and metformin ... —4 inhibitor, eGFR ... CKD #management #treatment
Metformin in Diabetic Kidney Disease
Immediate release:
 • Initial 500 mg or 850 mg once daily
 •
Metformin in Diabetic ... maximum dose eGFR ... recommended dose eGFR ... < 30: Stop metformin ... annually if on metformin
Metformin 
Current Renal Dose Adjustments due to Risk of Lactic Acidosis 
> 60 No adjustment 
45-60
Metformin Current ... 45-60 Monitor eGFR ... already taking metformin ... /ambcarerx #Metformin
The GFR Clock for Staging CKD

Staging CKD is most frequently done by calculating the estimated glomerular
The GFR Clock for ... function rate (eGFR ... calculating the eGFR ... to remember the eGFR ... #Nephro #CKD #EGFR
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... not initiate if eGFR ... not continue if eGFR ... EricsMedicalLectures/ #Metformin
Metformin - oral antihyperglycemic agent for treatement of type II diabetes. 8th most prescribed drug in
Metformin - oral ... antihyperglycemic agent for treatement ... #Pharmacology #Metformin
Metformin Treatment in Patients With Type 2 Diabetes and Chronic Kidney Disease Stages 3A, 3B, or
Metformin Treatment ... /dc17-2231 #Metformin
Diabetes Combination Tablets - Estimated A1c Lowering 
Metformin + DPP4 
• Janumet (metformin + sitagliptin) 
•
A1c Lowering Metformin ... DPP4 • Janumet (metformin ... • Jentadueto (metformin ... • Kombiglyze (metformin ... saxagliptin) Metformin
Interpreting Kidney Biomarkers

↑ Creatinine: 
 • AKI, CKD
 • Medications that lead to nephroprotective ↓ in
nephroprotective ↓ in GFR ... hyperthyroidism ↓ eGFR