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management product reactions acidosis cvid dermatology elevation extravascular fever hemolysis hodgkins hypogammaglobulinemia immunodeficiency infectiousdiseases intravascular lactate lactic lymphoma nonpalpable oncology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... microangiopathy: Thrombotic thrombocytopenic ... purpura (TTP), ... #differential # ... diagnosis #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... DIC/TTP/HUS - Hemolytic ... anemia - Splenomegaly ... deficiency • Liver ... Diagnosis #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Liver diseases ... and autoimmune hemolytic ... anemia) • Systemic ... DDX - Other causes ... #hematology #diagnosis
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
maculopapular rash, pruritis ... Causes purpura & ... severe thrombocytopenia ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Causes purpura & ... severe thrombocytopenia ... eruptions, diarrhea, liver ... #Transfusions #diagnosis ... #management #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Pruritis ... nodosum • Immune hemolytic ... Immunohistochemical studies (to differentiate ... number of sites of disease ... #hematology #oncology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
most common causes ... removal from the blood ... presentations and disease ... of Circulatory System ... #Diagnosis #causes
Fever After International Travel Infectious Disease: • Endemic in either the destination or home region Viral Syndromes: Arboviral infections, a
infections, a common ... No hemolytic anemia ... including tests of liver ... renal function • Blood ... Fever #Travel #Differential
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