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algorithm injury management transaminitis acidosis aflp aih ascites chemistry chronic cirrhosis comparison dili druginduced elevated encephalopathy erythematosus fatigue gap globulin
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Acute Liver Injury ... - Autoimmune ... disease - Hemochromatosis ... #Causes #Differential ... #Hepatology #Diagnosis
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... hepatitis, Acute ... #Diagnosis #Causes ... #hepatology
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
Nonalcoholic fatty liver ... (Budd-Chiari syndrome ... #Differential # ... Hepatology #Cirrhosis ... #Causes
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 Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Non-Malignant • Fatty Liver ... Hemochromatosis • Wilson's Disease ... • Budd-Chiari Syndrome ... • Autoimmune ... #Causes #Hepatology
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
Trauma: Shock liver ... Metabolic: Wilson Disease ... • Autoimmune ... Diagnosis #causes ... #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
for alternative causes ... disease, Hepatic ... dechallenge • Acute ... steatosis • Autoimmune ... #Algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Vascular Causes ... of Acute Liver ... Autoimmune hepatitis ... #hepatology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
Autoimmune Hepatitis ... from subclinical disease ... to acute liver ... (rare) - IgG Elevation ... #Hepatology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Renal Failure • Liver ... Neoplastic / Hematologic ... • HIV Autoimmune ... Obstructive Pulmonary Disease ... Chronic Fatigue Syndrome
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
disease: > 2 ... • Gilbert's syndrome ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
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