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vasculitis cryofibrinogenemia cryoglobulins erythematosus gap lupus management myopathy myositis protein proteingap sjogrens sle systemic types vasculitides
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... diseases: - 10% ... #types #classification ... #rheumatology #
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cold insoluble globulin ... associated with autoimmune ... Antiphospholipid syndrome ... #rheumatology # ... hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
renal tubular acidosis ... Nephrogenic DI Hematologic ... Vasculitis: • 7%, Cryoglobulinemia ... Arthralgia and Arthritis ... #Rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... permanent alopecia Differential ... • Non-autoimmune ... rheumatologic diseases ... #Rheumatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... changes (POEMS syndrome ... (RA, Temporal arteritis ... gastric tumors • Hematology ... #diagnosis #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Diagnosis Framework ... tract, and often causes ... ANCA +MPO) • Cryoglobulinemic ... #diagnosis #rheumatology ... #classification
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential ... • Nonerosive arthritis ... statins - probably caused ... Myositis #Myopathy #rheumatology ... #differential #
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