16 results
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Hyperviscosity Syndrome ... Cryoglobulinemia Syndrome ... cryoglobulinemia syndrome ... 20% Sjögren's syndrome ... #rheumatology #
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Creatinine & BUN: • Chronic ... : • Lymphoma ... Myelodisplastic syndrome ... Pruritus #primary #secondary ... #dermatology #Differential
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
to Systemic Diseases ... discoloration) • Chronic ... • Nephrotic syndrome ... #Secondary #dermatology ... #Differential #
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
processes: • Systemic ... • Negative causes ... Antiphospholipid syndrome ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
infection risk secondary ... DDX - Other causes ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... hypogammaglobulinemia #immunology #hematology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
: • Lymphoma ... Myelodisplastic syndrome ... #Pruritus #secondary ... #systemic #generalized ... #dermatology #Differential
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Epidemiology: • Most common ... cells can indicate disease ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
dermatomyositis, Sjogren syndrome ... • Evans' syndrome ... lymphoproliferative syndrome ... Shrinking lung syndrome ... Erythematosus #Diagnosis #Rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome ... Systemic disease ... tests in Behcet syndrome ... adenopathy (PFAPA) syndrome ... signs #symptoms #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Mucocutaneous lymph node syndrome ... VASCULITIS: • Behçet Syndrome ... • Cogan Syndrome ... #diagnosis #rheumatology ... #classification