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diagnosis hemolytic abnormal agglutinin algorithm aptt autoimmune coagulation cold elevatedmcv elevation erythematosus hemolysis intravascular lactic lupus macrocytic macrocytosis myopathy myositis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... - Drugs (Beta lactam ... #Causes #differential ... #diagnosis #hematology ... #anemia
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Volume (MCV) - Differential ... Increased Requirement (e.g ... Myelodysplastic Syndromes ... #Hematology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Causes of Lactate ... presentations and disease ... of Circulatory System ... - Compartment syndrome ... 30mmHg) - Severe anemia
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Hyperbilirubinemia • Elevated lactate ... younger pts) Differential ... the RBCs causing intravascular ... #hematology #diagnosis
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Early liver disease ... antiphospholipid antibodies ... associated with systemic ... #diagnosis #differential ... #hematology #coagulation
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... lymphopenia, low PLT • Anemia ... Erythematosus #Diagnosis #Rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... • Conduction system ... inflammation • Extramuscular ... statins - probably caused ... Myositis #Myopathy #rheumatology
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