14 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Idiosyncratic Drug-induced ... Chronic - ongoing ↑ LFTs ... Idiosyncratic #differential ... gastroenterology #algorithm
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... Diagnosis Algorithm ... • Others #LFTs ... #Differential #
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... valproate, azoles), Drugs ... #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Diagnosis Algorithm ... Chronic Disease (e.g ... Deficiency • Drugs ... #Causes #Hematology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Diagnosis Algorithm ... Burak @kwburak #LFTs ... #diagnosis #hepatology
Causes of Tremors - Movement Disorders - Differential Diagnosis Algorithm
Action Tremor - Occurs During Voluntary Muscle
Diagnosis Algorithm ... Cerebellar Disease (e.g ... Etiology (Thyroid, Liver ... , Kidney) • Drugs ... #Differential #
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Causes of Fatigue - Differential ... Diagnosis Algorithm ... Renal Failure • Liver ... Neoplastic / Hematologic ... Abuse (e.g.
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Algorithmic Approach ... Orotic aciduria, Drugs ... (e.g., hydroxyurea ... Non-megaloblastic: Liver ... Diagnosis #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Diagnosis Algorithm ... Congenital - Rare • Drugs ... (e.g. ... Iatrogenic) • Liver ... #Causes #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Volume (MCV) - Differential ... Diagnosis Algorithm ... Blood Smear • Drugs ... Increased Requirement (e.g ... #Causes #Hematology