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diagnosis causes abnormal bruising coagulation pt activation anemia classification dermatology disorders hemostasis macrophage management mas mcv naildisorders platelet rheumatology secondary
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Early liver disease ... Reduced liver synthesis ... associated with systemic ... #diagnosis #differential ... #hematology #coagulation
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Diagnosis Algorithm ... Rare • Drugs (e.g ... Iatrogenic) • Liver ... #Causes #Hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... • Reduced liver ... associated with systemic ... #diagnosis #differential ... #hematology #coagulation
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Diagnosis Algorithm ... 80-100 fL) • Bleeding ... (e.g. ... Renal Disease, Liver ... #Causes #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... - History of bleeding ... cases: INR/PT, aPTT ... (liver disease, ... disease), HBsAg
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
of Hemostasis - Differential ... the PT remains prolonged ... suggests liver ... Bruising #Hemostasis #Differential ... #Diagnosis #Hematology
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
halt nail growth (e.g ... discoloration) • Liver ... #Secondary #dermatology ... #Differential # ... Diagnosis #Algorithm
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
purpura to mucosal bleeding ... (eg, systemic juvenile ... thrombocytopenia • Liver ... Hypofibrinogenemia • ↑ PT ↑ PTT ... Diagnosis #Management #Hematology
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