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diagnosis syndrome neurology myasthenia rheumatology activation arteritis cell encephalopathy essential et gangrenosum gca giantcell macrophage mas oncology pg photo plasmacytoma
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Acquired von Willebrand ... Lymphoproliferative disorders (e.g ... Myeloproliferative disorders (e.g ... #treatment #hematology ... #differential
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Clinical Picture ... life-threatening Differential ... dystrophy - Brain stem ... Serologic and EMG ... #diagnosis #management
Myasthenia Gravis - Summary • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
Myasthenia Gravis ... serologic, and EMG ... characteristic EMG ... #Myasthenia #Gravis ... #diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
the secondary or acquired ... underlying disease (eg ... • Infection (eg ... Treatment: • Corticosteroids ... #Hematology #Rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... not be subtle e.g ... very remarkable w/differential ... E.g. 80 yo ESR cutoff ... Symptoms #Diagnosis #Management
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... and lower jaw Treatment ... antiinflammatory properties e.g ... #diagnosis #management ... #Dermatology
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
• Thrombosis (e.g ... ET-associated mutation (e.g ... thrombocytosis (e.g ... Thrombocythemia #ET #hematology ... #hematology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
bone marrow or stem ... Reversible course Differential ... • EEG: With persistent ... epilepticus Treatment ... Syndrome #diagnosis #management
Pyoderma Gangrenosum (PG) 50 M Crohn’s dz had a small pustule on the ankle 4 mo ago
wide variety of clinical ... Management of PG ... corticosteroid (eg ... PG secondary treatment ... #photo #dermatology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
plasmacytoma) Clinical ... red bone marrow, e.g ... Bone marrow Treatment ... chemotherapy as required ... Diagnosis #Workup #Hematology
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