5 results
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
and Workup Step ... Step 2. ... • nephrotic syndrome ... #Diagnosis #Workup ... #Algorithm #Nephrology
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis Workup ... Algorithm 1) ... renal mechanism 2) ... , Cushing syndrome ... #Algorithm #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Compartment syndrome ... Dermatomyositis Clinical Features ... Hyperuricemia • Hyponatremia ... nephrotoxicity to kidney ... causes #treatment #nephrology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... Heart, lung, and kidney ... 10,000 ng/mL • Hyponatremia ... Increased soluble IL-2 ... MAS #Macrophage #Activation
Hyponatremia Differential Diagnosis Algorithm in Cancer
UOsm ≥ 100 mOsm/kg = Urine is inappropriately concentrated for hypotonic
Diagnosis Algorithm ... appropriate • Hypovolemia ... CAR-T- and IL-2- ... capillary leak syndrome ... #nephrology #oncology