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management neurology syndrome comparison differential guillain symptoms als amyotrophic antinxp2 antinxp2dm dermatology dermatomyositis gbs guillainbarre hematology inflammatory lateral leukostasis lysis
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Pathophysiology ... Clinical Features ... Diagnosis: • ... demyelination features ... #Syndrome #diagnosis
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
• Associated Features ... • Associated Features ... • Associated Features ... • Associated Features ... #table
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... worrisome EKG features ... Syndrome #TLS #diagnosis ... #management #hematology
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... • The cardinal features ... the underlying pathophysiology ... and cauda equina TREATMENT ... GBS #Guillain #Barre
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism In contrast to the
Features That Differentiate ... associated with rheumatologic ... Pericarditis #Symptoms #Signs ... Presentation #comparison #Table ... #Diagnosis
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 Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... of UMN and LMN signs ... and with limb features ... EMG: LMN Signs in ... column Treatment
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... survival is 93-95% Pathophysiology ... failure Clinical Features ... Self-limiting, chronic but stable ... #Management #Signs
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Alterations: - Sensory features ... bouts of HTN Diagnostic ... • Bilateral signs ... Transverse Myelitis Treatment
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
chest (in a V-sign ... shoulders (in a shawl sign ... and Biological Features ... positive patients Treatment ... #management #rheumatology
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