10 results
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Pathogenesis and clinical ... Incr Skeletal fractures ... • Short stature ... sleep apnea, cor pulmonale ... #genetics #pathophysiology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Pathophysiology ... meningococcal, H1N1) Clinical ... Guillain-Barre Clinical ... : Starts in legs ... #diagnosis #management
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... survival is 93-95% Pathophysiology ... renal failure Clinical ... Pulmonary: dyspnea ... anterior/posterior MSK
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
Thiamine Deficiency - Differential ... Framework and Clinical ... HF • Moderate pulmonary ... Manifestations #Differential ... beriberi #nutrition #pathophysiology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
GrepMed Handbook Clinical ... coarsening facial features ... malignancy Pathophysiology ... Differential Diagnosis ... Beckwith Wiedemann syndrome
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
to be in ADHF starts ... with presence of pulmonary ... acute coronary syndrome ... #diagnosis #differential ... #algorithm #management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... noncompliance • Clinical ... initiation Clinical ... #Differential # ... Diagnosis #Management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Transverse Myelitis - Clinical ... Alterations: - Sensory features ... Myelitis #diagnosis #management ... #neurology #differential
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
salivary ducts Clinical ... Features: HEENT ... , INC risk PE, Pulmonary ... phenomenon (16%) MSK ... Rheumatology #Diagnosis #Management
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
tubule (DCT) Clinical ... Hypocalciuria (spot ... ratio 0.5%) Differential ... diagnosis #nephrology #management ... #pathophysiology