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oncology algorithm anticoagulation chemotherapy malignancy treatment vte anthracycline apixaban carcinoma cardiology cardiotoxicity cyp3a4 dabigatran diabetes diagnosis dm2 dosing dpp4 endocrinology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓) of cytochrome p450 CYP3A4 and P-glycoprotein. DOACs are substrates
) Cancer-treatment ... inducers (↑) and inhibitors ... #Chemotherapy #Oncology ... #Hematology #Interactions ... #Table #Pharmacology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis. Currently, edoxaban and rivaroxaban are the only
anticoagulants (DOACs ... filtration rate; DOAC ... #Cancer #Algorithm ... Anticoagulation #Management ... #Hematology #Oncology
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 Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
Anticoagulants - Pathophysiology ... heparin (UFH): Inhibits ... the function of ... heparin (LMWH): Functions ... #Pharmacology #Pathophysiology
Treatment algorithm for VTE in Malignancy (A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
thrombosis in cancer ... DOAC, direct oral ... #DOAC #VTE #Malignancy ... Anticoagulation #Management ... #Hematology #Oncology
DPP4 Inhibitors - Normal and Renal Dosing Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
DPP4 Inhibitors ... has very minimal chance ... check the kidney function ... Renal #Dosing #Pharmacology ... #Management #Diabetes
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... B-LNH), solid cancers ... Anti-IFN-y and JAK inhibitors ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Systemic Therapy for Hepatocellular Carcinoma - AGA Clinical Practice Guideline First Line Treatment for HCC with Preserved
Preserved Liver Function ... Systemic #Treatment #Management ... #Hepatology #Gastroenterology ... #oncology #Pharmacology
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity Anthracyclines cause cardiomyopathy: ✖ Reduction in left ventricular ejection fraction
Management of Anthracyclines ... ventricular ejection fraction ... system (RAAS) inhibitor ... Cardiotoxicity #cardiology #oncology ... #pharmacology #
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