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diagnosis hematology oncology leukemia management anemia bleeding chronic classification cll gap globulin hemostasis hodgkins lymphocytic lymphoma mds myelodysplasia myelodysplastic protein
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... specific loss-of-function ... Constitutional Syndromes ... #Anemia #oncology ... #hematology #diagnosis
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
PLT: Petechiae, bruising ... thrombocytopenia, or functional ... • Tumor lysis syndrome ... lymphoid organs When Cancer ... #Leukemia #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... Pure red cell aplasia ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
Bleeding and Bruising ... of Hemostasis - Differential ... von Willebrand syndrome ... causes are liver function ... #Diagnosis #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Easy or unusual bruising ... Causes • Anemia • Aplastic ... blood count with differential ... #diagnosis #hematology ... #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
hematological malignancy arising ... from germinal center ... Immunohistochemical studies (to differentiate ... classification #hematology ... #oncology #management
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
changes (POEMS syndrome ... ovarian tumors, lung cancers ... gastric tumors • Hematology ... Gap #ProteinGap #differential ... #diagnosis #hematology
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