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diagnosis hematology oncology lupus druginduced syndrome activation anemia aplastic apml blood chronic cll comparison differentiation dil erythematosus gravis hemeonc heparin
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
Heparin Induced ... skin necrosis (at injection ... Confirmatory test ↑Se ... #HIT #Heparin #Induced ... #Treatment #Hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... vs SLE Drug Induced ... is rare in DIL, SCLE-DIL ... comparison #table #rheumatology ... #diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus [SLE ... ], AOSD) • Infection ... Sepsis • Drug-induced ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
rheumatoid arthritis, SLE ... Miller Fischer and PCB ... Penicillamine induced ... precipitated by: Drugs, infection ... Gravis #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
erythematosus (SCLE ... Non-autoimmune rheumatologic ... fibromyalgia) • Infections ... La, anti-Jo-1, SCL ... Antihistone: Drug induced
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... endothelial damage • Induce ... Differential Diagnosis: Infection ... fluid overload, PCC ... APML #diagnosis #management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... weeks without infection ... Neutropenia, anemia, thrombocytopenia ... microglobulin Treatment ... Transform to DLBCL, PML
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
/fevers • Thrombocytopenia ... Idiopathic • Infections ... cells is much reduced ... aplastic anemia Treatment ... #diagnosis #management
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
purpura & severe thrombocytopenia ... • Infection - ... , Trypanosoma (Chagas ... Transfusions #diagnosis #management ... #hematology #reactions
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
platelet count (thrombocytopenia ... petechiae) • Frequent infections ... IDUS) • Immune Thrombocytopenia ... • Parvovirus infection ... cells have DNA changes
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