11 results
Validation of the Step-By-Step Approach to Febrile Infants

#Diagnosis #Management #Pediatrics #Peds #Febrile #Infant #StepByStep #Algorithm #LP
#Diagnosis #Management ... #Pediatrics #Peds ... #Febrile #Infant ... #Antibiotics #Risk ... Stratification #Fever
“Step by Step” – the new kid on the block – aims to risk stratify this
” an infant with ... Procalcitonin <0.5 ng/mL ... CRP < 20 mg/L #Diagnosis ... #Management #Pediatrics ... #Peds #Febrile
Step by Step Algorithmic Approach to Pediatric Fever

Age < 21 days old (or 28 days for
Procalcitonin >= 0.5 ng/mL ... #Pediatrics #Peds ... #Diagnosis #Management ... StepByStep #Algorithm #Infant ... #Fever
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
frequently affects infants ... following: • Fever ... Ferritin >500 ng/mL ... #management #treatment ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... Ferritin >1000 ng/ml ... sIL-2R >2400 Ul/ml ... #management #treatment ... #summary #rheumatology
The Febrile Infant Step-by-Step Algorithm
This is an algorithm developed by European emergency physicians to identify low-risk
to identify low-risk ... 92.0% and 46.9% #Diagnosis ... #EBM #Management ... #Pediatrics #Peds ... Stratification #Fever
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lymphohistiocytosis (HLH ... - Nonremitting fever ... 5000 to 10,000 ng/mL ... Activation #Syndrome #Diagnosis ... #Management #Hematology
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
locations: Wrist, MCP ... inflammatory response Risk ... 12-24 Hours • Fever ... Gout #Comparison #rheumatology ... #Diagnosis
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma Risk ... • Dyspnea • Fever ... (MCHL) - Lymphocyte ... classification #hematology ... #oncology #management
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
locations: Wrist, MCP ... culture used to diagnose ... acute neck pain, fever ... Deposition #Disease #Rheumatology ... #diagnosis #management