10 results
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia ... overt cytoplasmic granules ... , and Auer rods. ... features in most cases ... KyleBradleyMD #Auer
Here are very large, immature myeloblasts with many nucleoli. A distincitve feature of these blasts is
a linear red "Auer ... of crystallized granules ... acute myelogenous leukemia ... Smear #Microscopy #Auer
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
abundant cytoplasmic granules ... promyelocytic leukemia ... decreased secondary granules ... acute myeloid leukemia ... mixed lineage leukemia
Differential diagnosis on HRCT
Most of our knowledge about imaging findings in interstitial lung disease comes from
there are four patterns ... low attenuation (table ... The cystic pattern ... When the cysts have ... seen and in many cases
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... , CLL Acute leukemias ... Chronic leukemia ... Age: 50-60 • Auer ... distinctive primary granules
Low Attenuation pattern 
1. Lymphangiomyomatosis (LAM): uniform cysts in woman of child-bearing age; no history of
Low Attenuation pattern ... (LAM): uniform cysts ... bizarre shaped cysts ... LowAttenuation #Cystic #Pattern ... #Comparison #Table
Low Attenuation pattern (2) 
1. Centrilobular emphysema: low attenuation areas without walls. Notice the centrilobular artery
Low Attenuation pattern ... multiple thick walled cysts ... (LAM): regular cysts ... LowAttenuation #Cystic #Pattern ... #Comparison #Table
Nodular pattern(2)
1. Sarcoidosis: nodules with perilymphatic distribution, along fissures, adenopathy.
2. TB: Tree-in-bud appearance in a patient
Nodular pattern( ... before the typical cysts ... CTChest #Nodular #Pattern ... #Comparison #Table
On the left some diseases with a nodular pattern.
1. Hypersensitivity pneumonitis: ill defined centrilobular nodules.
2. Miliary
with a nodular pattern ... before the typical cysts ... CTChest #Nodular #Pattern ... Differential #Comparison #Table
Anaplastic large cell lymphoma, ALK+
Clinical
 • First 3 decades of life, M>F
 • Often nodal +
variant can have leukemic ... • Small cell pattern ... • Hodgkin-like pattern ... • Composite pattern ... than one • Rare cases