12 results
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... Lymphoproliferative Disorders, Infection ... , Interstitial Pulmonary ... ANA #patterns #rheumatology ... #diagnosis #differential
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
life-threatening diseases ... EGPA) • Auto-antibodies ... confirm DAH, r/o infection ... #differential # ... diagnosis #management #treatment
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
gland) biopsy • Histo ... salivary ducts Clinical ... Adenocarcinoma Treatment ... lubricants • Pharmacologic ... #Rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
progressing GN • New pulmonary ... + MPO-ANCA MEDIUM ... to exclude are infections ... C-ANCA) pattern: antibodies ... #diagnosis #rheumatology
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
requires special media ... antimicrobials, clinical ... for antinuclear antibodies ... antiphospholipid syndrome ... Diseases Fellows
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
published cases, Median ... Relapsing-remitting course +++ Clinical ... filling +++ (risk of pulmonary ... of infections) ... #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... primary condition MEDIUM ... affects the skin, neurologic ... cognitive impairment, neurologic ... #Diagnosis #Rheumatology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... worsening of that disease ... a few months (median ... Lymphadenitis, pulmonary ... #Differential #
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
starts with a good history ... with presence of pulmonary ... acute coronary syndrome ... #diagnosis #differential ... #pharmacology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
symptoms • Rheumatologic ... has five major clinical ... fungal stain of clinical ... for Blastomyces antibodies ... for Coccidioides antibodies