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diagnosis rheumatology management ana antinuclear bcnie bloodculture classification cryofibrinogenemia endocarditis immune infective inflammatory iris negative nontuberculous ntm patterns prs reconstitution
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
progressing GN • New pulmonary ... tract, and often causes ... + MPO-ANCA MEDIUM ... to exclude are infections ... C-ANCA) pattern: antibodies
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Autoimmune ANCA vasculitis ... EGPA) • Auto-antibodies ... confirm DAH, r/o infection ... Goodpasture's cause ... #differential #
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... Hematologic malignancy ... History of immunosuppressive ... Disease: Clinical ... #differential #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... primary condition MEDIUM ... tract, and often causes ... #Rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
microscopy and serial ... likely it will be clinically ... Lymphoproliferative Disorders, Infection ... , Interstitial Pulmonary ... #diagnosis #differential
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... gland) biopsy • Histo ... salivary ducts Clinical ... : • 10%-15% Pulmonary ... Nephrogenic DI Hematologic
Blood Culture-Negative Infective Endocarditis (BCNIE) Definition: No etiology found after 3 separate blood cultures remain negative for
requires special media ... antimicrobials, clinical ... but important causes ... antiphospholipid syndrome ... Diseases Fellows
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
malignancies, vasculitis ... Malignancy • Infections ... thrombophlebitis, pulmonary ... Antiphospholipid syndrome ... #hematology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... worsening of that disease ... a few months (median ... organizing PNA • Mycobacterium ... #Differential #
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