11 results
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential ... tract, and often causes ... Coronary arteries - Fever ... • Cogan Syndrome ... purpura: strong sign
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Leg Pain - Differential ... abscess - Herpes zoster ... pain/swelling - Fever ... #Leg #pain #differential ... lower #extremity #msk
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
polymorphisms alter ... various inflammatory cells ... periumbilical region), nausea ... nephrotic/nephritic syndrome ... Pathophysiology #Diagnosis #Signs
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... purpura: Strong sign ... Multinucleated giant cells ... tract, and often causes
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Hypertension - Workup and Differential ... hypertension and signs ... renal bruit or signs ... Coarctation of aorta, Vasculitis ... #Differential #
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
tissue: Epithelioid cells ... anterior/posterior MSK ... Specific sarcoidosis syndromes ... • Heerfordt syndrome ... Diagnosis #Management #Signs
Hearing Loss - Differential Diagnosis Framework

Hearing Loss Types:
• Conductive
• Sensorineural
• Mixed
Presbycusis is the most common type
Hearing Loss - Differential ... • Stroke • Vasculitis ... II ○ Susac’s syndrome ... Noise trauma ○ MS ... Hearing #Loss #Differential
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... e.g., uptake by cells ... / hypoxemia -> focus ... - Compartment syndrome ... Acidosis #Elevation #Differential
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
back pain at/near level ... • Bilateral signs ... defined sensory level ... - Sjogren - Vasculitis ... management #neurology #differential
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... ) • Cutaneous vasculitis ... : 10%-16% Liver ... : 2% Systemic Vasculitis ... phenomenon (16%) MSK