16 results
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
IgA Vasculitis – ... polymorphisms alter ... various inflammatory cells ... nephrotic/nephritic syndrome ... Pathophysiology #Diagnosis #Signs
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
Hematuria - Differential ... Glomerular Bleeding - IgA ... hematuria • Signs ... Diagnostic of GN or vasculitis ... #Hematuria #Differential
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... • Ig A vasculitis ... Vasculopathy #Purpura #Differential
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... purpura: Strong sign ... Multinucleated giant cells ... tract, and often causes ... , IgA (cmpkx deposits
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential ... Schonlein Purpura (IgA ... tract, and often causes ... Coronary arteries - Fever ... purpura: strong sign
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Leg Pain - Differential ... abscess - Herpes zoster ... pain/swelling - Fever ... #Leg #pain #differential ... lower #extremity #msk
Fever Patterns - Differential Diagnosis Framework

Continuous Fever:
Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... Non-Infectious Causes ... • Hyper-IgD syndrome ... Brucellosis Faget's Sign ... #Patterns #Differential
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Cold Agglutinin Syndrome ... malignancies -> CLL (older ... younger pts) Differential ... sensitize red blood cells
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Bilateral signs ... defined sensory level ... • Infectious causes ... - Sjogren - Vasculitis ... management #neurology #differential
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Hypertension - Workup and Differential ... hypertension and signs ... renal bruit or signs ... Coarctation of aorta, Vasculitis ... #Differential #