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neurology differential hematology treatment als amyotrophic arteritis chronic cll gca giantcell lateral leukemia leukostasis lymphocytic lysis ms multiple myelitis neuritis
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Clonus, Babinski’s sign ... • Lhermitte’s sign ... pupillary defect SIGNS ... Signs and symptoms ... #diagnosis #management
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
of UMN and LMN signs ... of UMN and LMN signs ... both UMN and LMN signs ... EMG: LMN Signs in ... #management
Optic Neuritis - Diagnosis and Management • Epidemiology: Female (75%), 18-50 years, caucasian • Symptoms: Moderate visual
Optic Neuritis - Diagnosis ... and Management ... caucasian • Symptoms ... Unilateral • Signs ... #rheumatology #
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... WBC >100k, + lab signs ... Lysis of tumor cells ... Syndrome #TLS #diagnosis ... #management #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Affects mainly older ... with no early symptoms ... Physical Exam/Signs ... phenomenon CLL Diagnosis ... Lymphocytic #Leukemia #diagnosis
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... them, but urgent rheumatology ... GCA #Temporal #Signs ... #Symptoms #Diagnosis ... #Management
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Bilateral signs ... and/or symptoms ... Pleocytosis > 100 cells ... : - Multiple sclerosis ... #management #neurology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... and Management ... tissue: Epithelioid cells ... anterior/posterior MSK ... #Management #Signs
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... , particularly scleritis ... purpura: Strong sign ... • Progressive symptoms ... #Rheumatology
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